![Aggregation of PolyQ35 protein in C. elegans is suppressed by NAC. ... Copyright: Karina Gense Aggregation of PolyQ35 protein in C. elegans is suppressed by NAC. The images show the head region of worms expressing a Huntington’s disease related polyglutamine-expanded protein (PolyQ35). Overexpression of NAC in the worm (right image) prevents aggregation and toxicity of PolyQ35. Copyright: Karina Gense](/fileadmin/pi/fileserver/2019/Bilder/NAC_a_highly_potent_suppressor.jpg)
Protein complex prevents toxic aggregation of proteins
A protein complex within the cell has been found to play a key role in preventing the toxicity of proteins which build up amyloid plaques and can lead to neurodegenerative disorders such as Alzheimer’s and Huntington’s disease.
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