Mayr MI, Storch M, Howard J, Mayer TU (2011)
A Non-Motor Microtubule Binding Site Is Essential for the High
Processivity and Mitotic Function of Kinesin-8 Kif18A.
PLoS One. 6(11):e27471.

Florian S, Mayer TU. (2011) Modulated microtubule dynamics
enable Hklp2/Kif15 to assemble bipolar spindles.
Cell Cycle. 10(20):3533-44.

Hamecher J, Rieß T, Bertini E, Kozak K, Kastl J, Mayer TU,
Merhof D (2011) A Versatile Framework for the Analysis of
High-Throughput Screening Data , Dorit Merhof 8th Int.
Workshop on Computational Systems Biology (WCSB)
pp. 57-60; HiTSEE

Bertini E, Strobelt H, Braun J, Deussen O, Groth U, Mayer TU,
Merhof D (2011) A Visualization Tool for Hit Selection and
Analysis in High-Throughput Screening Experiments.
1st IEEE Symposium on Biological Data Visualization
(IEEE BioVis) (accepted)

Benz A, Singh V, Mayer TU, Hartig JS (2011) Identification of
Novel Quadruplex Ligands from Small Molecule Libraries by
FRET-Based High-Throughput Screening. Chembiochem.
June 14, 12(9):1422-26

Sironi L, Solon J, Conrad C, Mayer TU, Brunner D,
Ellenberg J. (2011) Automatic quantification of microtubule
dynamics enables RNAi-screening of new mitotic spindle
regulators. Cytoskeleton May 68:266–278

Hörmanseder E, Tischer T, Heubes S, Stemmann O, Mayer TU.
(2011) Non-proteolytic ubiquitylation counteracts the
APC/C-inhibitory function of XErp1.
EMBO Rep. May 1;12(5):436-43.

Strittmatter T, Bareth B, Immel TA, Huhn T, Mayer TU,
Marx A. (2011)Small Molecule Inhibitors of Human DNA Poly-
merase λ.ACS Chem Biol. Apr 15;6(4):314-9

Mayer TU, Marx A. (2010)
Five molecules we would take to a remote island.
Chem Biol., 17(6):556-60

Mitterreiter S, Page RM, Kamp F, Hopson J, Winkler E, Ha HR,
Hamid R, Herms J, Mayer TU, Nelson DJ, Steiner H, Stahl T,
Zeitschel U, Rossner S, Haass C, Lichtenthaler SF. (2010)
Bepridil and amiodarone simultaneously target the Alzheimer's
disease beta- and gamma-secretase via distinct mechanisms.
J Neurosci, 30(26):8974-83.

Svetlik J, Veizerová L, Mayer TU, Catarinella M. (2010)
Monastrol analogs: a synthesis of pyrazolopyridine, benzo-
pyranopyrazolopyridine, and oxygen-bridged azolopyrimidine
derivatives and their biological screening.
Bioorg Med Chem Lett., 20(14):4073-6. Epub 2010 May 26.

Catarinella M, Grüner T, Strittmatter T, and Mayer TU. (2009).
BTB-1: a small molecule inhibitor of the mitotic motor protein
Kif18A. Angew Chem Int Ed Engl, 48 (48), 9072-9076

Hümmer S and Mayer TU.(2009). Cdk1 Negatively
Regulates Midzone Localization of the Mitotic Kinesin Mklp2
and the Chromosomal Passenger Complex.
Curr. Biol.[Epub ahead of print]

Mayr, M., Hümmer, S., Bormann, J., Grüner, T., Adio, S.,
Woehlke, G., and Mayer, T.U. (2007). The human kinesin
Kif18A is a motile microtubule depolymerase essential for
chromosome congression. Curr. Biol., 17, 488-498.

Lessmann, T., Leuenberger, M.G., Menninger, S.,
Lopez-Canet, M., Müller, O., Hümmer, S., Bormann, J.,
Korn, K., Fava, E., Zerial, M., Mayer, T.U., and  Waldmann, H.
(2007). Natural product- derived modulators of cell cycle
progression and viral entry by enantioselective oxa Diels-Alder
reactions on the solid phase. Chem Biol., 14, 443-451.

Schust, J., Sperl, B., Hollis, A., Mayer, T.U., and Berg, T. (2006).
Stattic: a small-molecule inhibitor of STAT3 activation and
dimerization. Chem Biol. 11, 1235-1242.

Rauh, N.R., Schmidt, A., Bormann, J., Nigg, E.A., and Mayer, T.U.
(2005). Calcium triggers exit from meiosis II by sensitising the
APC/C inhibitor XErp1 for Plx1-dependent degradation.
Nature, 437, 1048-1052.

Sunder-Plassmann, N., Sarli, V., Gartner, M., Utz, M., Seiler, J.,
Huemmer, S., Mayer, T.U., Surrey, T., and  Giannis. A. (2005).
Synthesis and Biological Evaluation of new Tetrahydro-β-
carbolines as Inhibitors of the Mitotic Kinesin Eg5.
Bioorg. Med. Chem., 22, 6094-6111.

Sarli, V., Sunder-Plassmann, N., Huemmer, S., Mayer, T.U.,
and Giannis, A. (2005). Development and Biological Evaluation
of a new class of Inhibitors of Mitotic Kinesin Eg5.
Chembiochem,11, 2005-2013. 

Barun, O., Sommer, S., Kumar, K., Langerak, A., Mayer, T.U.,
Müller, O., and Waldmann, H. (2005). Enantioselective
Solid-Phase Synthesis of Spiro[5.5]ketals.
Eur. J. Org. Chem. 4773–4788.

Schmidt, A., Duncan, P.I., Rauh, N.R., Sauer, G., Fry, A.M.,
Nigg, E.A., and Mayer, T.U. (2005). Xenopus polo-like kinase
Plx1 regulates XErp1, a novel inhibitor of APC/C activity.
Genes Dev., 15, 502-513.

Perlman, Z.E., Mitchison, T.J., and Mayer, T.U. (2005).
High-content screening and mechanistic profiling of
drug activity in an automated centrosome duplication
assay. Chembiochem., 6, 145-151.

Hotha, S., Yarrow, J.C., Yang, J.G., Garrett, S.,
Renduchintala, K.V., Mayer, T.U., and Kapoor, T.M. (2003).
HR22C16: A Novel Anti-Mitotic Agent and Small Molecule
Probe for the Dynamics of Cell Division.
Angew Chem Int Ed Engl., 42, 2379-2382.

Neef, R., Preisinger, C., Sutcliffe, J., Kopajtich, R., Nigg, E.A.,
Mayer, T.U., and Barr, F.A. (2003). Phosphorylation of
mitotic kinesin-like protein 2 by polo-like kinase 1 is
required for cytokinesis. J. Cell Biol., 162, 863-875.

Kapoor, T.M., Mayer, T.U., Coughlin, M.L., and
Mitchison, T.J. (2000). Probing spindle assembly
mechanisms with monastrol, a small molecule inhibitor
of the mitotic kinesin, Eg5. J. Cell Biol., 150, 975-988.

Tournebize, R., Popov, A., Kinoshita, K., Ashford, A.J.,
Rybina, S., Mayer, T.U., Walczak, C.E., Karsenti, E., and
Hyman A.A. (2000). Control of microtubule dynamics
requires the antagonistic activities of XMAP215 and
XKCM1. Nature Cell Biol., 2, 13-19.

Mayer, T.U., Kapoor, T.M., Haggarty, S.J., King, R.W.,
Schreiber, S.L., and Mitchtison, T.J. (1999). Small molecule
inhibitor of spindle bipolarity identified in a phenotype-
based screen. Science, 286, 971-974.

Haggarty, S.J., Mayer, T.U., Miyamoto, D., Mitchison, T.J.,
Schreiber, S.L. (1999). Dissecting cellular processes using
small molecules: identification of colchicine-like, taxol-like
and other small molecules that perturb mitosis.
Chem Biol., 4, 275-286.

Koegl, M., Hoppe, T., Schlenker, S., Ulrich, H.D., Mayer, T.U.,
and Jentsch, S.(1999). A novel ubiquitination factor, E4, is
involved in multiubiquitin chain assembly. Cell, 96, 635-644.

Mayer, T. U., Braun, T., and Jentsch, S. (1998). Role of the
proteasome in membrane extraction of a short-lived ER-
transmembrane protein. EMBO J.,17, 3251-3257.

Review article

Florian, S., Catarinella, M., Hümmer, S., and Mayer, T.U. (2007).
Chemical Genetics:  Reshaping Biology through Chemistry.
HFSP Journal, accepted.

Florian, S., Hümmer, S., and Mayer, T.U. (2006).
Chemische Biologie, Biospektrum, 05, 606

Berg, T., Mayer, T.U., and Frank, R. (2006). Chemische Biologie.
Im Trendbericht über „Biochemie und Molekularbiologie“.
Nachrichten aus der Chemie, 3, 265-276.

Schmidt, A., Rauh, N.R., and Mayer, T.U. (2005). Cytostatic
factor: an activity that puts the cell cycle on hold.
J. Cell Science, 119, 1213-1218. 

Mayer, T.U. (2003). Chemical genetics: Tailoring tools for cell
biology. Trends Cell Biol., 13, 270-277.