Publications 1995 - 2006
| 1995 |
|
| 1 |
Bräutigam, M., M. Klein, R. Knippers & D. G. Müller (1995) Inheritance and meiotic elimination of a virus genome in the host Ectocarpus siliculosus (Phaeophyceae). J. Phycol. 31, 823 - 827 |
| 2 |
Burkhart, R., D. Schulte, B. Hu, C. Musahl, F. Göring & R. Knippers (1995) Interactions of the human nuclear proteins P1Mcm3 and P1Cdc46. Eur. J. Biochem. 228, 431 - 438 |
| 3 |
Halmer, L., and C. Gruss. (1995). Influence of histone H1 on the in vitro replication of DNA and chromatin. Nucl. Acids Res. 23, 773-778 |
| 4 |
Heiland, S. & R. Knippers (1995) The human topoisomerase I gene promoter is regulated by NF-IL6. Mol Cell. Biol. 15, 6623 - 6631 |
| 5 |
Kilwinski, J., M. Baack, S. Heiland & R. Knippers (1995) Transcription factor Oct1 binds to the AT-rich segment of the simian virus 40 replication origin. J. Virol. 69, 575 - 578 |
| 6 |
Klein, M., S. Lanka, R. Knippers & D. G. Müller (1995) Coat protein of the Ectocarpus siliculosus Virus. Virology 206, 520 - 526 |
| 7 |
Musahl, C., D. Schulte, R. Burkhart & R. Knippers (1995) A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins. Eur. J. Biochem. 230, 1096 - 1101 |
| 8 |
Ramsperger, U., & H. Stahl (1995) Unwinding of chromatin by the SV40 large T antigen DNA helicase. EMBO 14, 3215 – 3225 |
| 9 |
Schulte, D., R. Burkhart, C. Musahl, B. Hu, C. Schlatterer, H. Hameister & R. Knippers (1995) Expression, phosphorylation and nuclear localization of the human P1 protein, a homologue of the yeast Mcm3 replication protein. J. Cell Sci. 108, 1381 - 1389 |
| 1996 |
|
| 10 |
Halmer, L., and C. Gruss. (1996). Effects of cell-cycle dependent histone H1 phosphorylation on chromatin structure and chromatin replication. Nucl. Acids Res. 24, 1420-1427 |
| 11 |
Holthoff, H.P., H. Hameister & R. Knippers (1996) A novel human Mcm protein : homology to the yeast replication protein Mis5 and chromosomal location. Genomics 37, 131 - 134 |
| 12 |
Krude, T., C. Musahl, R. A. Laskey & R. Knippers (1996) Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S phase and are displaced locally during DNA replication. J. Cell Sci. 109, 309 - 318 |
| 13 |
Müller, D.G., M Sengco, S. Wolf, M. Bräutigam, C.E. Schmid, M. Kapp & R. Knippers (1996) Comparison ot two DNA viruses infecting the marine brown algae Ectocarpus siliculosus and E. Fasciculatus. J. Gen. Virol. 77, 2329 - 2333 |
| 14 |
Müller, D.G., M. Bräutigam & R. Knippers (1996) Virus infection and persistence of foreign DNA in the marine brown alga Feldmannia simplex (Ectocarpales, Phaeophyceae) Phycologia 35, 61 - 63 |
| 15 |
Paul, R., B. Hu, C. Musahl. H. Hameister & R. Knippers (1996) Coding sequence and chromosome mapping of the human gene CDC46 for replication protein hCdc46/Mcm5. Cytogenet. Cell Genet. 73, 317 - 321 |
| 16 |
Quintini, G., K. Treuner, C. Gruss & R. Knippers (1996) Role of amino-terminal histone domains in chromatin. Mol. Cell. Biol. 16, 2888 - 2897 |
| 17 |
Renz, A., F.O. Fackelmayer (1996) Purification and molecular cloning of the scaffold attachment factor B (SAF-B), a novel human nuclear protein that specifically binds to S/MAR-DNA . Nucleic Acid Research 24:843 - 849 |
| 18 |
Schulte,
D., A. Richter, R. Burkhart, C. Musahl & R. Knippers (1996) Properties
of the human nuclear protein p85Mcm. Expression, nuclear localization
and interaction with other Mcm proteins. Eur. J. Biochem. 235, 144 - 151
|
| 19 |
Treuner, K., U. Ramsperger & R. Knippers (1996) Replication protein A induces the unwinding of long double-stranded regions. J. Mol. Biol. 259, 104 - 112 |
| 1997 |
|
| 20 |
Alexiadis, V., L. Halmer, and C. Gruss. (1997). Influence of core histone acetylation on SV40 minichromosomes replication in vitro. Chromosoma 105, 324-331 |
| 21 |
Göhring, F , & F.O. Fackelmayer (1997) The Scaffold/Matrix Attachment Region Binding Protein hnRNP-U (SAF-A) Is Directly Bound to Chromosomal DNA in Vivo: A Chemical Cross-linking Study, Biochem. 8276 - 8283 |
| 22 |
Göhring,
F., B.L. Schwab, P. Nicotera, M. Leist, & F.O. Fackelmayer (1997)
The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is
a target in apoptotic nuclear breakdown. EMBO 16, 7361 - 7261 |
| 23 |
Halmer, L., and C. Gruss. (1997). Accessibility for topoisomerase I and II regulates the replication efficiency of SV40 minichromosomes in vitro. Mol. Cell. Biol. 17, 2624-2630 |
| 24 |
Kapp, M., R.Knippers,D.G. Müller (1997) New member of a group of DNA viruses infecting brown algae. Phychol. Res. 45, 85-90 |
| 25 |
Ladenburger, E. M., F. O. Fackelmeyer, H. Hameister &
R. Knippers (1997) MCM4 and PRKDC, human genes encoding proteins Mcm4
and DNA-PKcs, are close neighbours located on chromosome 8q12-q13. Cytogenet.
Cell Genet. 77, 268 - 270 |
| 26 |
Richter, A. & R. Knippers (1997) High-molecular-mass
complexes of human minichromosome- maintenance proteins in mitotic cells.
Eur. J. Biochem. 247, 136 - 141 |
| 27 |
San
Martin, C., C. Gruss, and J.M. Carazo
(1997). Six molecules of SV40 large T antigen assemble in a propeller-shaped
particle around a channel. J. Mol. Biol. 114, 167-176 |
| 28 |
Schwab, B. L., M. Leist, R. Knippers & P. Nicotera (1997) Selective proteolysis of the nuclear replication factor MCM3 in apoptosis. Exp. Cell Res. 238, 415 - 421 |
| 29 |
Wang, Z., C. Zimmer, J. W. Lown & R. Knippers (1997)
Effects of bifunctional netropsin-related minor groove - binding ligands
on mammalian type I DNA topisomerase. Biochem. Pharmacol. 53, 309 - 316 |
| 1998 |
|
| 30 |
Alexiadis, V., P. Varga-Weisz., E. Bonte, P.B. Becker and C. Gruss (1998).Chromatin remodeling by CHRAC at the SV40 origin of DNA replication. EMBO J. 17,3428-3438 |
| 31 |
Halmer,
L. and C. Gruss (1998) Involvement of Topoisomerasees in the Initiation
of Simian Virus 40 Minichromosome Replication. J Biol Chem. 274, 34792-34798
|
| 32 |
Holthoff, H.P., M. Baack, A. Richter, M. Ritzi & R. Knippers
(1998) Human protein MCM6 on HeLa cell chromatin. J. Biol. Chem. 273,
7320-7325 |
| 33 |
Musahl, C., H.P. Holthoff, R. Lesch & R. Knippers (1998)
Stability of the replicative Mcm3 protein in proliferating and differentiating
human cells. Exp. Cell Res. 241, 260-264 |
| 34 |
Richter, A., M. Baack, H.P. Holthoff, M. Ritzi & R. Knippers
(1998) Mobilization of chromatin-bound Mcm proteins by micrococcal nuclease.
Biol. Chem. 379, 1181-1187 |
| 35 |
Ritzi,
M., M. Baack,C. Musahl, P. Romanowski, R.A. Laskey & R. Knippers (1998)
Human Mcm proteins and human ORC2 protein on chromatin. J. Biol. Chem.
273, 24543-24549 |
| 36 |
Schwab, B.L., M. Leist, R. Knippers & P. Nicotera (1998)
Selective proteolysis of the nuclear replication factor MCM3 in apoptosis.
Exp. Cell Res. 238, 415-421 |
| 37 |
Treuner, K., C. Eckerich & R. Knippers (1998) Chromation
association of replication protein A. J. Biol. Chem. 273, 31744-31750 |
| 38 |
Vestner, B., M. Bustin, and C. Gruss (1998). Stimulation of replication efficiency of a chromatin template by chromosomal protein HMG-17. J. Biol. Chem. 273, 9409-9414 |
| 39 |
Zhang,
J.J., Y. Zhao, B.T. Chait, W.W. Lathem, M. Ritzi, R. Knippers & J.E. Darnell
(1998) Ser727- dependent recruitment of MCM5 by Stat1_ in IFN-_-induced
transcriptional activation. EMBO J. 17, 6963-6971 |
| 1999 |
|
| 40 |
Delaroque, N., I. Maier, R. Knippers & D.G. Müller (1999)
Persistent virus intergration into the genome of its algal host, Ectocarpus
siliculosus (Phaeophyceae). J. Gen. Virol. 80: 1367-1370 |
| 41 |
Findeisen,
M., M. El-Denary, T.Kapitza, R. Graf & U. Strausfeld (1999) Cyclin
A dependent kinase activity affects chromatin binding of O’RC, Cdc6,
and MCM in egg extracts of Xenopus laevis. |
| 42 |
Kipp, M., B. L. Schwab, M. Przybylski, P. Nicotera & F.O. Fackelmayer (1999) Apoptotic Cleavage of Scaffold Attachment Factor A (SAF-A) by Caspase-3 Occurs at a Non-Canonical Cleavage Site. J. Biol. Chem. 275, 5031 – 5036 |
| 43 |
Treuner, K., A. Okuyama, R. Knippers & F.O. Fackelmayer
(1999) Hyperphosphorylation of Replication Protein A middle subunit (RPA32)
in apoptosis. Nucleic Acids Research 27(6), 1499-1504 |
| 44 |
Treuner,
K., M. Findeisen, U. Strausfeld & R. Knippers (1999) Phosphorylation of
Replication Protein A Middle Subunit (RPA32) Leads to a Disassembly of
the RPA Heterotrimer. J. Biol. Chem. 274(22), 15556-15561 |
| 2000 |
|
| 45 |
Alexiadis, V., T. Waldmann, J. Andersen, M. Mann, R. Knippers & C. Gruss (2000) The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin-specific manner. Genes & Develop. 14, 1308 - 1312 |
| 46 |
Delaroque,
N., S. Wolf, D.G. MŸller & R. Knippers (2000) Characterization and immunolocalization
of major structural proteins in the brown algal virus EsV-1. Virology
269, 148 -155 |
| 47 |
Delaroque,
N., S. Wolf, D.G. MŸller & R. Knippers (2000) The brown algal virus EsV-1-particle
contains a putative hybrid histidine kinase. Virology 273, 383-390 |
| 48 |
Kipp, M., F. Göhring, Th. Ostendorf, C.M. van Drunen, R. van Driel, M. Pryzybilski & F.O. Fackelmayer (2000) SAF-Box, a Conserved Protein Domain That Specifically Recognizes Scaffold Attachment Region DNA. Mol. Cell. Biol. 20, 7480 - 7489 |
| 49 |
Kreitz,
S., F.O. Fackelmayer, J. Gerdes & R. Knippers (2000) The proliferation-specific
human Ki-67-protein is a constituent of compact chromatin, Exp. Cell Res.
261, 284-292 |
| 50 |
Vestner,
B., Waldmann, T. and Gruss, C. (2000) Histone Octamer Dissociation Is
Not Required for in Vitro Replication of Simian Virus 40 Minichromosomes.
J. Biol. Chem. 275(11), 8190-8195 |
| 2001 |
|
| 51 |
Birner, P., M. Ritzi, C. Musahl, R. Knippers, J. Gerdes, T. Voigtländer, H. Budka & J.H. Hainfellner (2001) Immunohistochemical detection of cell growth fraction in formalin fixed and paraffin embedded murine tissue. Am. J. Pathol. 158, 1991-1996 |
| 52 |
Delaroque, N., D.G. Müller, G.Bothe, T. Pohl, R. Knippers & W. Boland (2001) The complete nucleotide sequence of the Ectocarpus siliculosus virus. Virology, 287, 112-132 |
| 53 |
Eckerich, C., F.O. Fackelmayer & R. Knippers (2001) Zinc affects the conformation of nucleoprotein filaments formed by replication protein A (RPA) and long natural molecules. Biochim. Biophys. Acta,1538, 67-75 |
| 54 |
Endl, E., I. Kausch, M. Baack, R. Knippers, J. Gerdes & T. Scholzen (2001) The expression of Ki-67, MCM3 and p27 defines subsets of proliferating, resting and differentiated cell. J. Patholog., J. Patholog. 195, 457-462 |
| 55 |
Jahr, S., H. Hentze, D. Hardt, F.O. Fackelmayer, S. Englisch, H.D. Hesch & R. Knippers (2001) On the origin of DNA fragments in the plasma of tumor patients: quantitation of tumor DNA and apoptotic cell death. Cancer Research, 61,1659-1665 |
| 56 |
Kappes,
F., Burger, K., Baack, M., Fackelmayer, F.O. and C. Gruss. (2001). Subcellular
localization of the human proto-oncogene protein DEK. J. Biol. Chem.,
276, 26317-26323 24. |
| 57 |
Kreitz,
S., M. Ritzi, M. Baack & R. Knippers (2001) The human origin recognition
proteins 1 and 2 (hOrcp1 and hOrc2p) on HeLa cell chromatin. J. Biol.
Chem.,276, 6337-6342 |
| 2002 |
|
| 58 |
Biermann, E., M.Baack, S. Kreitz & R. Knippers (2002)
Synthesis and turn-over of the replicative Cdc6 protein during the HeLa
cell cycle. Eur. J. Biochem. 269, 1040-1046 |
| 59 |
Keller,
C., O. Hyrien, R. Knippers &T. Krude (2002) Site-specific and temporally
controlled initiation of DNA replication in a human cell-free system.
Nucleic Acids Res. 30 2114-2123 |
| 60 |
Keller, C., E.M. Ladenburger, M. Kremer & R. Knippers (2002) The Origin Recognition Complex Marks a Replication Origin in the Human TOP1 Gene Promoter. J. Biol. Chem. 277, 31430-31440 |
| 61 |
Ladenburger,
E.M., C.Keller & R. Knippers (2002) Identification of a binding region
for the human origin recognition complex (ORC) proteins 1 and 2 that coincides
with an origin of DNA replication. Mol.Cell.Biol., 22,1036-1048 |
| 62 |
Schaarschmidt, D., E.M. Ladenburger, C. Keller & R. Knippers (2002) Human Mcm proteins at a replication origin during G1 to S phase transition. Nucl. Acids Res. 4176-4185 |
| 63 |
Waldmann, T., Eckerich, C, Baack, M, and C. Gruss. (2002). The ubiquitous chromatin protein DEK alters the structure of DNA by introducing positive supercoils. J. Biol. Chem., 277, 24988-24994 |
|
|
| 64 |
Delaroque, N., W. Boland, D.G. Müller & R.Knippers (2003) Comparisons of two large phaeoviral genomes and evolutionary implications. J. Mo. Evo. 57, 613-622 |
| 65 |
Gozuacki, D., M. Chami, D. Lagorce, J. Faivre, Y. Murakami, O. Poch, E. Biermann, R. Knippers, C. Bréchot & P. Paterlini-Bréchot (2003) Identification and functional characterization of a new member of the human Mcm protein family : hMcm8. Nucl. Acids Res. 31, 570 – 57 |
66 |
Waldmann, T., M. Baack, N. Richter & C. Gruss (2003) Structure-specific binding of the proto-oncogene proteine DEK to DNA. Nucl.Acids Res. 31, 7003-7010 |
| 67 |
Kulartz, M., S. Kreitz, E. Hiller, E. C. Damoc, M. Przybylski & R. Knippers (2003) Expression and phosphorylation of the replication regulator protein geminin. Biochem. Biophys. Res. Comm. 305, 412 – 420 |
| 2004 |
|
68 |
Kappes,
F., C. Damoc, R. Knippers, M. Przybylski, L.A. Pinna & C. Gruss (2004)
Phosphorylation by protein kinase CK2 change the DNA binding properties
of human chromatin protein DEK. |
69 |
Kappes, F., I. Scholten, N. Richter, C. Gruss & T. Waldmann (2004) Functional domains of the ubiquitous chromatin protein DEK. Mol. Cell Biol.24, 6000-6010 |
70
|
Kulartz, M., E. Hiller, F. Kappes, L. A. Pinna & R. Knippers (2004) Protein kinase CK2 phosphorylates the cell cycle regulatory protein Geminin. Biochem. Biophys. Res. Comm. 315, 1011 - 1017 |
| 71 |
Schaarschmidt, D., J. Baltin, I. M. Stehle, H. J. Lipps & R. Knippers (2004) An episomal mammalian replicon : sequence-independent binding of the origin recognition complex. EMBO J. 23, 191 – 201 |
72 |
Kulartz, M. & R. Knippers (2004) The Replicative Regulator Protein Geminin on chromatin in the HeLa Cell Cycle. J Biol. Chem. 279, 41686 – 41694 |
73 |
Ito, E., D. Sahri, R. Knippers & E. Carstens (2004) Baculovirus proteins IE-1, LEF-3, and P143 interact with DNA in vivo: a formaldehyde cross-linking study. Virology 329, 337 – 347 |
2005 |
|
74 |
Böhm, F., F. Kappes, I Scholten, N. Richter, H. Matsuo, R. Knippers & T. Waldmann (2005) The SAF-box domain of chromatin protein DEK. Nucl. Acids Res. 33, 1101-1110 |
75 |
Hu, H.-G., H. Illges, C. Gruss & R. Knippers (2005) Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre-and mature B lymphocytes. Intern. Imm. 17, 789 - 796 |
2006 |
|
| 76 | Baltin, J, S. Leist, F. Odronitz, H.P. Wollscheid, M. Baack, T. Kapitza, D. Schaarschmidt & R. Knippers (2006) DNA replication in protein extracts from human cells requires ORC and MCM proteins. J. Biol. Chem. 281, 12428-12435 |
| 77 | Tabbert,A. F.Kappes, R. Knippers, J. Kellermann, F. Lottspeich, E. Ferrando-May (2006) Hypophosphorylation of the architectural chromatin protein DEK in death-receptor-induced apoptosis revealed by the isotope coded protein label proteomic platform. Proteomics. 6 (21), 5758-72. |
Reviews
| Gruss,
C. & R. Knippers (1995) The SV40 minichromosome. Methods Mol. Genet. 7,
101 -113 |
| Gruss,
C. & R. Knippers (1996) Structure of replicating chromatin. Progr. Nucleic
Acids Res. Mol. Biol. 52, 337 - 365 |
| Klebl,
A.K., M. Bräutigam, M. Klein, M. Kapp, R. Knippers & D.G. Müller (1996)
Molecular and biochemical studies of virus infections in two filamentous
brown algae. Hydrobiologia 326/327, 105-110 |
| Müller,
D.G., M. Kapp & R. Knippers (1998) Viruses in marine brown algae. Adv. Virus
Res. 50, 49-67 |
| Gruss,
C. (1999). In vitro replication of chromatin templates, p. 291. In P.Becker
(ed.), Methods in Molecular Biology Vol. 119, Humana press, New York. |
| Ritzi,
M. & R. Knippers (2000) Initiation of genome replication: assembley and
disassembly of replication competent chromatin. Gene 245, 13-20 |
| Müller,
D.G. R. Knippers (2002) Phaeovirus (Phycodnaviridae), pp732-736. In: Tidona,
C.A. and Darai G. (Eds) The Springer Index of Viruses. Springer Verlag Berlin
Heidelberg NewYork Tokyo pp, 732 - 737 |
| Waldmann, T., I. Scholten, F. Kappes, H.-G. Hu & R. Knippers (2004) The DEK protein: an abundant and ubiquitous constituent of mammalian chromatin. Gene, 343, 1 - 9 |
| Knippers, R. (1998)
Genetik heute: In. Spektrum der Wissenschaft, pp 92-96, Juni-Heft |
| Knippers, R. (1999)
Reden über die neue Genetik des Menschen. In der Reihe "Konstanzer Universitätsreden",
Band 200, Universitätsverlag Konstanz |
| Knippers, R. (2001)
Molekulare Genetik. 8. Auflage. Ein Lehrbuch.Georg Thieme Verlag, Stuttgart |
| Knippers, R. (2001)
Erwin Baur. Eine wissenschafltiche Biographie. BioSpektrum 1,43-45 |
| Knippers, R. (2001)
Historisches Portrait: Eugen Fischer - Die Korruption der Wissenschaft durch
den Zeitgeist. BioSpektrum 6, 37-39 |
| Knippers, R. (2002)“Liegt
unser Schicksal in den Genen? Das Human-Genom-Projekt und seine Bedeutung
für Wissenschaft und Gesellschaft“, SS. 55 – 70. In: E.
Beck (Hrgb) Faszination Lebenswissenschaften. Wiley-VCH, Weinheim |
| I.M. Stehle & D. Schaarschmidt (2005) Autonom replizierende Vektors für Säugetierzellen. BioSpektrum 11, 162-165 |
| Knippers, R. (2005) Rückblicke: die Gesellschaft für Genetik und ihre Anläufe zu einem Internationalen Genetik-Kongress in Deutschland. Biospektrum 11, 310-311 |
| Knippers, R. (2006) Molekulare Genetik. Ein Lehrbuch. 9. Auflage.Georg Thieme Verlag, Stuttgart |